Summary
UNR/CSDE1 is an RNA-binding protein that promotes melanoma invasion and metastasis.
According to its function in post-transcriptional regulation, UNR localizes primarily in the cytoplasm. However, the detailed intracellular localization of UNR (e.g. its association with particular cellular organelles) is unclear. Here, we have used confocal and super-resolution microscopy together with biochemical fractionation to study the localization of UNR in
melanoma cells.
We find novel and described associations of UNR within the cytoplasmic compartment.
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The Barcelona Institute of Science and Technology is a multidisciplinary research institute formed by the alliance of seven top research centers in Barcelona commited to creating a collaborative environment of multidisciplinary scientific excellence.
