BIST-Dolors-Aleu-Graduate-Centre
Jorge Cordero

Jorge

Cordero

MMRES student at DCEXS and ICFO
Class 2019-2020

P4-ATPases interact with Multisubunit Tethering Complexes to regulate vesicle trafficking in Saccharomyces cerevisiae

Summary

A novel short motif has been discovered at the N-terminus of some P4 ATPases in Saccharomyces cerevisiae. The study of the interactions mediated by this motif in the lipid ippase Drs2 suggests that this peptidic sequence is fundamental for the regulation of vesicle tracking at the trans-Golgi network and, especially, in Atg9 mediated autophagy.

Major project supervisor

Oriol Gallego
CRG

Minor project supervisor

Felix Campelo
ICFO